I'm right now listening to one of David's 4 videos on the future of space exploration. And this guy's got the knowledge - Wikipedia says about him:
In 1973, he graduated from the California Institute of Technology with a Bachelor of Science in astrophysics. He followed this with a Master of Science in applied physics in 1978 and a Doctor of Philosophy in space science in 1981, both from the University of California, San Diego.
Brin is a 2010 fellow of the Institute for Ethics and Emerging Technologies. He helped establish the Arthur C. Clarke Center for Human Imagination (UCSD). He serves on the advisory board of NASA's Innovative and Advanced Concepts group and frequently does futurist consulting for corporations and government agencies.
On the subject of Mars, he's thinking of the 'expedition' profile of mission, not the 'one-way-ticket' espoused by Mars One and others. Still lots of common sense - cache supplies, use resources out there, formulate a wise overall goal for space exploration that will work economically. Warning: you need time and spare brain power to listen to this guy.